Article: Properties of the nucleo-olivary pathway: an in vivo whole-cell patch clamp study.
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Bazzigaluppi P; Ruigrok T; Saisan P; De Zeeuw CI; de Jeu M
PLoS ONE, 2012
10.1371/journal.pone.0046360.t002
Sub- and supra-threshold responses in Control and with presence of GABAA receptors blocker (DNDS).
|
|
Control |
GABAA blocker DNDS |
|
Oscill. behavior |
Immediately after break-in |
>20 minutes after break in |
p- value |
n |
Immediately after break-in |
>20 minutes after break in |
p- value |
n |
Short latency EPSP (%)
|
LTO |
34.3±10 |
32.6±11.8 |
0.80 |
6 |
49.1±27.1 |
36.1±14.6 |
0.19 |
7 |
|
SSTO |
16.7±2 |
43.0±1.9 |
0.49 |
3 |
86.1±13.2 |
56.4±19 |
0.14 |
4 |
Long latency IPSP (%)
|
LTO |
93.6±7.9 |
87.5±3.8 |
0.11 |
6 |
85.3±11.4 |
25.4±10.6 |
<0.01 |
7 |
|
SSTO |
83.8±3.9 |
81.9±11.2 |
0.88 |
3 |
93.5±4.7 |
39.9±14.4 |
<0.01 |
4 |
IPSP duration (ms)
|
LTO |
512±187 |
518±161 |
0.90 |
6 |
390±26 |
295±14 |
0.02 |
7 |
|
SSTO |
334±179 |
376±138 |
0.38 |
3 |
219±19 |
198±26 |
0.42 |
4 |
IPSP peak amplitude (mV)
|
LTO |
-7.6±2.0 |
-6.0±1.9 |
0.18 |
6 |
-6.5±1.5 |
-3.4±1.0 |
<0.01 |
7 |
|
SSTO |
-8.2±2.7 |
-6.7±1.3 |
0.37 |
3 |
-10.96±3.9 |
-4.2±1.8 |
<0.01 |
4 |
IPSP surface area (ms*mV)
|
LTO |
2738±1806 |
2261±1268 |
0.57 |
6 |
1737±599 |
654±150 |
<0.01 |
7 |
|
SSTO |
1871±474 |
1896±458 |
0.27 |
3 |
1718±882 |
484±245 |
0.04 |
4 |
Rebound (%)
|
LTO |
60.1±32 |
57.4±28.3 |
0.21 |
6 |
68.2±21.2 |
69±17.3 |
0.46 |
7 |
|
SSTO |
87±9.7 |
84.2±5.7 |
0.25 |
3 |
96.5±1.4 |
74.2±10.5 |
<0.05 |
4 |
Rebound amplitude (mV)
|
LTO |
9.52±4.2 |
10.9±4 |
0.30 |
6 |
6.9±2.3 |
8.1±2.9 |
0.09 |
7 |
|
SSTO |
13.9±3.7 |
13.5±4.2 |
0.81 |
3 |
10.2±2.1 |
11.85±2.3 |
0.3 |
4 |
Inferred neuron-electrophysiology data values
Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |